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Topical ciprofloxacin in pregnancy

topical ciprofloxacin in pregnancy

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Drugs & Diseases

Brand and Other Names:Gyne Lotrimin, Lotrimin, more...Lotrimin AF, Mycelex topical

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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

topical cream/ointment/solution

  • 1%

vaginal cream

  • 1%
  • 2%

more...

Cutaneous Candidiasis/ Dermatophytosis

OTC products indicated for treatment of tinea pedis, tinea cruris, and tinea corporus

Prescription products indicated for Candida albicans and tinea versicolor, in addition to OTC product indications

Apply to affected area q12hr

If no improvement after 4 weeks, re-evaluate diagnosis

See also combo with betamethasone (Lotriderm/Lotrisone)

Vaginal Candidiasis

Cream (1%): Insert 1 applicatorful daily, preferably at bedtime, for 7-14 days

Cream (2%): Insert 1 applicatorful daily, preferably at bedtime, for 3 consecutive days

Superficial Dermatologic Infection

Apply to affected area q12hr for 7 consecutive days

Dosage Forms & Strengths

cream/ointment/topical solution

  • 1%

vaginal cream

  • 1%
  • 2%

more...

Cutaneous Candidiasis/Dermatophytosis

<12 years

  • Safety and efficacy not established

>12 years

  • OTC products indicated for treatment of tinea pedis, tinea cruris, and tinea corporis
  • Prescription products indicated for Candida albicans and tinea versicolor, in addition to OTC product indications
  • Apply to affected area q12hr
  • If no improvement after 4 weeks, re-evaluate diagnosis
  • See also combo with betamethasone (Lotriderm/Lotrisone)

Vaginal Candidiasis

<12 years

  • Safety and efficacy not established

>12 years

  • Cream (1%): Insert 1 applicatorful daily, preferably at bedtime, for 7-14 days
  • Cream (2%): Insert 1 applicatorful daily, preferably at bedtime, for 3 consecutive days

Superficial Dermatologic Infection

<12 years

  • Safety and efficacy not established

>12 years

  • Apply to affected area q12hr for 7 consecutive days

Adverse Effects

Frequency Not Defined

Blistering

Erythema

Edema

Pruritus

Burning

Stinging

Peeling

Urticaria

Skin fissures

General irritation of the skin

Elevated serum AST (SGOT) concentrations (15%)

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Warnings

Contraindications

Hypersensitivity to clotrimazole or components

Cautions

Avoid contact with eyes

Some dosage forms contain benzyl alcohol; large amounts of benzyl alcohol have been associated with gasping syndrome (potentially fatal) in neonates

Not for use by patients who have never had a vaginal infection diagnosed by a doctor

Not for use with tampons, douches, spermicides, or other vaginal products

Condoms and diagrams may damage and fail to prevent pregnancy or sexually transmitted disease

Not for use when having vaginal intercourse

May cause mild increase in vaginal burning, itching or irritation

Patient should ask doctor if symptoms do not get better in 3 days, symptoms last more than 7 days, or experience rash, abdominal pain, fever, chills, nausea, vomiting, or a foul smelling vagina discharge

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Pregnancy & Lactation

Pregnancy

Small amounts of imidazoles may be absorbed systemically following topical and vaginal administration

Lactation

Excretion in milk unknown; use with caution

Pregnancy Categories

more...

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Pharmacology

Mechanism of Action

Antifungal activity

Alters cell membrane permeability, apparently by binding with phospholipids in the fungal cell membrane, causing essential intracellular elements to leak

Absorption

Negligible through intact skin (3-10% absorbed with intravaginal dose)

Time to peak: 24 hr (vaginal cream)

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Images

loading Pricing and Images

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Patient Handout

activity indicator
activity indicator

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Formulary

FormularyPatient Discounts

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Create Your List of Plans

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
Plans
Non-Medicare Plans Medicare Plans

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Source: http://reference.medscape.com/drug/lotrimin-af-clotrimazole-topical-343486


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